Axel Grothey Selected Research

Oxaliplatin (Eloxatin)

1/2021	Clinical Validation of a Machine-learning-derived Signature Predictive of Outcomes from First-line Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer.
1/2021	Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial.
1/2021	Duration of Adjuvant Doublet Chemotherapy (3 or 6 months) in Patients With High-Risk Stage II Colorectal Cancer.
1/2021	Microsatellite Instability in Patients With Stage III Colon Cancer Receiving Fluoropyrimidine With or Without Oxaliplatin: An ACCENT Pooled Analysis of 12 Adjuvant Trials.
1/2021	Sex and Adverse Events of Adjuvant Chemotherapy in Colon Cancer: An Analysis of 34 640 Patients in the ACCENT Database.
8/2019	The Mechanism of Action of Regorafenib in Colorectal Cancer: A Guide for the Community Physician.
1/2019	Bolus 5-fluorouracil (5-FU) In Combination With Oxaliplatin Is Safe and Well Tolerated in Patients Who Experienced Coronary Vasospasm With Infusional 5-FU or Capecitabine.
3/2018	Duration of Adjuvant Chemotherapy for Stage III Colon Cancer.
1/2018	Optimizing Adjuvant Therapy for Localized Colon Cancer and Treatment Selection in Advanced Colorectal Cancer.
1/2018	Challenges of conducting a prospective clinical trial for older patients: Lessons learned from NCCTG N0949 (alliance).

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Axel Grothey Research Topics

Disease

130	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 05/2002
82	Neoplasms (Cancer) 01/2022 - 05/2002
43	Colonic Neoplasms (Colon Cancer) 11/2022 - 05/2005
18	Neoplasm Metastasis (Metastasis) 01/2022 - 08/2005
17	Disease Progression 01/2021 - 09/2006
11	Hypertension (High Blood Pressure) 01/2021 - 11/2008
11	Fatigue 01/2020 - 01/2013
8	Nausea 01/2021 - 01/2004
7	Microsatellite Instability 01/2021 - 07/2010
7	Peripheral Nervous System Diseases (PNS Diseases) 12/2016 - 05/2004
6	Diarrhea 01/2021 - 05/2004
6	Adenocarcinoma 01/2021 - 05/2008
5	Neutropenia 01/2021 - 01/2004
5	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2021 - 05/2004
4	Stomach Neoplasms (Stomach Cancer) 03/2021 - 06/2006
4	Vomiting 01/2021 - 05/2004
4	Rectal Neoplasms (Rectal Cancer) 01/2021 - 11/2018
3	Anemia 01/2021 - 07/2019
3	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 01/2021 - 06/2014
3	Stomatitis 01/2021 - 01/2004
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2020 - 05/2008
3	Exanthema (Rash) 10/2019 - 01/2013
3	Neurologic Manifestations (Neurological Manifestations) 01/2018 - 08/2003
2	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 06/2020
2	Thrombocytopenia (Thrombopenia) 01/2021 - 06/2015
2	Glioblastoma (Glioblastoma Multiforme) 06/2020 - 05/2008
2	Pain (Aches) 01/2020 - 05/2013
2	Proteinuria 01/2020 - 06/2015
2	Fever (Fevers) 10/2019 - 01/2012
2	Chest Pain (Chest Pains) 01/2019 - 01/2018
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2019 - 05/2008
2	Cardiotoxicity 01/2019 - 01/2018
2	Lung Neoplasms (Lung Cancer) 01/2018 - 05/2008
2	Liver Diseases (Liver Disease) 01/2018 - 01/2015
2	Breast Neoplasms (Breast Cancer) 01/2016 - 12/2009
2	Alopecia (Baldness) 12/2006 - 01/2004
2	Hand-Foot Syndrome 05/2004 - 01/2004

Drug/Important Bio-Agent (IBA)

39	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2021 - 08/2003
38	Fluorouracil (Carac)FDA LinkGeneric 01/2021 - 01/2004
25	Bevacizumab (Avastin)FDA Link 01/2021 - 04/2005
19	regorafenibIBA 01/2021 - 05/2012
18	Leucovorin (Folinic Acid)FDA Link 01/2021 - 04/2004
15	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2005
15	Irinotecan (Camptosar)FDA LinkGeneric 01/2021 - 04/2004
13	Cetuximab (Erbitux)FDA Link 01/2021 - 09/2005
13	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 10/2006
13	ErbB Receptors (EGF Receptor)IBA 01/2020 - 11/2005
11	AntibodiesIBA 01/2020 - 12/2006
10	Biological ProductsIBA 01/2019 - 08/2004
9	Capecitabine (Xeloda)FDA Link 01/2021 - 01/2004
9	Monoclonal AntibodiesIBA 01/2020 - 05/2006
7	Sodium Glutamate (Accent)IBA 01/2021 - 10/2007
5	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2018
5	Pharmaceutical PreparationsIBA 06/2020 - 10/2013
5	Panitumumab (Vectibix)FDA Link 12/2016 - 05/2006
4	Circulating Tumor DNAIBA 01/2022 - 10/2018
4	encorafenibIBA 01/2021 - 10/2019
4	binimetinibIBA 01/2021 - 10/2019
4	Proteins (Proteins, Gene)FDA Link 11/2020 - 01/2012
4	trifluridine tipiracil drug combinationIBA 01/2020 - 01/2016
4	XELOXIBA 01/2018 - 11/2006
3	Calcibiotic Root Canal SealerIBA 10/2021 - 01/2018
3	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 08/2015
3	pembrolizumabIBA 01/2021 - 01/2018
3	Tyrosine Kinase InhibitorsIBA 06/2020 - 03/2016
3	Sorafenib (BAY 43-9006)FDA Link 06/2020 - 02/2016
3	Gemcitabine FDA Link 01/2020 - 05/2008
3	Phosphotransferases (Kinase)IBA 08/2019 - 06/2014
3	PlatinumIBA 10/2017 - 07/2008
3	Epidermal Growth Factor (EGF)IBA 12/2016 - 09/2015
3	Paclitaxel (Taxol)FDA LinkGeneric 04/2015 - 07/2008
2	Lipase (Acid Lipase)FDA Link 01/2020 - 06/2015
2	LigandsIBA 07/2019 - 01/2018
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 07/2019 - 01/2012
2	Rituximab (Mabthera)FDA Link 10/2017 - 03/2005
2	Dexamethasone (Maxidex)FDA LinkGeneric 10/2017 - 02/2005
2	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 03/2016 - 01/2016
2	4-boronic acid benzophenoneIBA 07/2014 - 11/2008
2	MagnesiumIBA 04/2014 - 02/2011
2	CalciumIBA 04/2014 - 02/2011
2	Granisetron (Kytril)FDA LinkGeneric 02/2005 - 01/2005
2	AntiemeticsIBA 02/2005 - 01/2005
1	sotorasibIBA 01/2022
1	thiamine triphosphorate (TTP)IBA 01/2022
1	B7-H1 AntigenIBA 01/2022
1	adagrasibIBA 01/2022

Therapy/Procedure

106	Therapeutics 01/2022 - 05/2002
63	Drug Therapy (Chemotherapy) 03/2021 - 05/2002
19	Adjuvant Chemotherapy 11/2022 - 05/2002
7	Immunotherapy 01/2022 - 01/2016
3	Continuity of Patient Care 10/2020 - 01/2007
3	Radiotherapy 01/2018 - 01/2018
3	Palliative Care (Palliative Therapy) 05/2016 - 05/2002
3	Combination Drug Therapy (Combination Chemotherapy) 03/2010 - 08/2004
2	Precision Medicine 11/2020 - 09/2016
2	Salvage Therapy 01/2020 - 05/2004
2	Duration of Therapy 03/2018 - 09/2006
2	Metastasectomy 01/2018 - 01/2018
2	Biological Therapy 02/2013 - 04/2007
1	Transplantation 11/2021